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Home » Disease Information » Elevated liver enzymes

Elevated Liver Enzymes (ALT/AST)

Elevated liver enzymes Alanine aminotranferease (ALT) and aspartate aminotransferase (AST) are enzymes located in liver cells that leak out into circulating blood when liver cells are injured.

ALT and AST are found in other cells in the body, but their concentration is highest in liver cells. ALT and AST are also found in heart, skeletal muscle, and red blood cells. Certain medications, such as those taken to lower cholesterol, can have a damaging effect on the liver. These enzymes are often monitored in patients who are taking these medications.

Cholesterol-lowering medications

Some cholesterol-lowering medications include:

Statins:

Lipitor®
Zocor®
Mevacor®
Pravachol®
Lescol®
Crestor®
Advicor®
Caduet®
Vytorin®
lovastatin
pravastatin
simvastatin

Fibrates:

Tricor®
Lopid®
gemfibrozil

Nicotinic Acid

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Comments

Guy Lemire, MD, FRCS (C), FACS (THOR) said on July 27, 2010

Linda - Of course you can be helped! I recommend you consult an experienced internal medicine specialist with an interest in treating diseases of the liver. Some University hospitals often times have doctors who specialize in liver diseases only (they are called hepatologists).

Guy Lemire, MD, FRCS (C), FACS (THOR) said on July 27, 2010

For a male, the desirable range for ALT is 10-40 U/L and the desirable range for AST is 15-40 U/L. A more detailed explanation is available on this page: http://www.lifelinescreening.com/health-screening-services/elevated-liver-enzymes.aspx

Linda said on July 17, 2010

My liver enzymes are very high due to large doses of Tylenol..... I take fiorcet for my migraines , can be very addicting... and it has Tylenol in it.... I am 48 and my numbers came back 203, I am going to a liver Dr , can I be helped ? Or is there no hope ?

ROBERT said on July 02, 2010

What is the normal level of liver enzymes for a 55 yr.old

Guy Lemire, MD, FRCS (C), FACS (THOR) said on May 27, 2010

Sue - Yes, the liver is very resilient especially if you can remove the cause of the liver problem.

Sue said on May 08, 2010

due to lipitor, we were just told that my partners liver enzymes were elevated....once the liver is injured can it heal on its own? what else can we do?

Guy Lemire, MD, FRCS (C), FACS (THOR) said on May 03, 2010

Paige - I recommend that you talk to your doctor for a thorough history, physical, and some lab testing.

Paige said on April 19, 2010

I see where there are two types of enzymes. I'm not sure which one maybe both of mine are elevated. I have had a blood test now I am scheduled for a ultrasound. The # I remember is 70. I am 53. What could it mean?

Guy Lemire, MD, FRCS (C), FACS (THOR) said on April 07, 2010

Jessica - The best suggestion is that you bring your son to a Children's Hospital Clinic affiliated with a medical school.

jessica said on March 30, 2010

what dose it mean when 4 yr old son has high liver enzymes all over his life and cant find out why he has been to so many dr and they dont know wht they stay high for can u help me plz

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